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RESEARCH - ORIGINAL ARTICLES - MUSCLE AND ADIPOSE TISSUE



Culvenor AG, Hamler FC, Kemnitz J, Wirth W, Eckstein F

Loss of muscle strength prior to knee replacement: a question of anatomic cross-sectional area

or specific strength?

Arthritis and Rheumatology [Epub ahead of print] (2017)


Steidle-Kloc E, Culvenor AG, Dörrenberg J, Wirth W, Ruhdorfer A, Eckstein F

Relationship between knee pain and infra-patellar fat pad morphology - A within- and between-person analysis from the Osteoarthritis Initiative.

Arthritis Care and Research (2017) (Epub ahead of print)


Kemnitz J, Wirth W, Eckstein F, Ruhdorfer A, Culvenor AG

Longitudinal change in thigh muscle strength prior to and concurrent with symptomatic and radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative.

Osteoarthritis and Cartilage 25(10):1633-1640 (2017)


Burda B, Steidle-Kloc E, Dannhauer T, Wirth W, Ruhdorfer A, Eckstein F

Variance in infra-patellar fat pad volume: Does the body mass index matter?-Data from osteoarthritis initiative participants without symptoms or signs of knee disease.

Annals of Anatomy 213:19-24 (2017)


Kemnitz J, Eckstein F, Culvenor AG, Ruhdorfer A, Dannhauer T, Ring-Dimitriou S, Sänger AM, Wirth W

Validation of an active shape model-based semi-automated segmentation algorithm for the analysis of thigh muscle and adipose tissuecross-sectional areas.

MAGMA 30(5):489-503 (2017)


Pogacnik Murillo AL, Eckstein F, Wirth W, Beavers D, Loeser RF, Nicklas BJ, Mihalko SL, Miller GD, Hunter DJ, Messier SP
Impact of diet and/or exercise intervention on infrapatellar fat pad morphology: secondary analysis from the intensive diet and exercise for Arthritis (IDEA) Trial.
Cells Tissues Organs 203(4):258-266 (2017) 


Ruhdorfer A, Haniel F, Petersohn T, Dörrenberg J, Wirth W, Dannhauer T, Hunter DJ, Eckstein F
Between-group differences in infra-patellar fat pad size and signal in symptomatic and radiographic progression of knee osteoarthritis vs non-progressive controls and healthy knees - data from the FNIH Biomarkers Consortium Study and the Osteoarthritis Initiative.
Osteoarthritis and Cartilage 25(7):1114-1121 (2017) 

Culvenor AG, Boeth H, Diederichs G, Wirth W, Duda G, Eckstein F
Longitudinal bone, muscle and adipose tissue changes in physically active subjects - sex differences during adolescence and maturity.
Journal of Musculoskeletal and Neuronal Interactions 16(3): 237-246 (2016)

Steidle-Kloc E, Wirth W, Ruhdorfer A, Dannhauer T, Eckstein F
Intra- and inter-observer reliability of quantitative analysis of the infra-patellar fat pad and comparison between fat- and non-fat-suppressed imaging-Data from the Osteoarthritis Initiative.
Annals of Anatomy 204:29-35 (2016)

Ruhdorfer A, Wirth W, Dannhauer T, Eckstein F
Longitudinal (4 year) change of thigh muscle and adipose tissue distribution in chronically painful vs painless knees - data from the Osteoarthritis Initiative.
Osteoarthritis and Cartilage 23: 1348-1356 (2015)

Dannhauer T, Ruhdorfer A, Wirth W, Eckstein F
Quantitative relationship of thigh adipose tissue with pain, radiographic status, and progression of knee osteoarthritis: longitudinal findings from the Osteoarthritis Initiative.
Investigative Radiology 50:268-274 (2015)

Diepold J, Ruhdorfer A, Dannhauer T, Wirth W, Steidle E, Eckstein F
Sex-differences of the healthy infra-patellar (Hoffa) fat pad in relation to intermuscular and subcutaneous fat content - Data from the Osteoarthritis Initiative
Annals of Anatomy 200:30-36 (2015) 

Ruhdorfer A, Dannhauer T, Wirth W, Cotofana S, Roemer F, Nevitt M, Eckstein F, for the OAI investigators
Thigh muscle cross-sectional areas and strength in knees with early vs knees without radiographic knee osteoarthritis: a between-knee, within-person comparison.
Osteoarthritis and Cartilage 22:1634-1638 (2014)

Sattler M, Dannhauer T, Ring-Dimitriou S, Sänger AM, Wirth W, Hudelmaier M, Eckstein F
Relative distribution of quadriceps head anatomical cross-sectional areas and volumes - sensitivity to pain and to training intervention.
Annals of Anatomy 196:464-470 (2014) 

Ruhdorfer A, Wirth W, Hitzl W, Nevitt M, Eckstein F; for the OAI investigators
Thigh muscle strength is associated with knee symptoms but not with radiographic disease stage of osteoarthritis - data from the Osteoarthritis  Initiative.
Arthritis Care and Research (Hoboken) 66:1344-1353 (2014)

Dannhauer T, Sattler M, Wirth W, Hunter DJ, Kwoh CK, Eckstein F

Longitudinal sensitivity to change of MRI-based muscle cross-sectional area versus isometric strength analysis in osteoarthritic knees with and without structural progression: pilot data from the Osteoarthritis Initiative.

Magnetic Resonance Materials in Physics, Biology and Medicine 27:339-347 (2014)


Eckstein F, Hitzl W, Duryea J, Kent Kwoh C, Wirth W; OAI investigators

Baseline and longitudinal change in isometric muscle strength prior to radiographic progression in osteoarthritic and pre-osteoarthritic knees ? data from the Osteoarthritis Initiative.


Osteoarthritis and Cartilage 21:682-690 (2013)

Ruhdorfer A, Dannhauer T, Wirth W, Hitzl W, Kwoh CK, Guermazi A, Hunter DJ, Benichou O, Eckstein F

Thigh muscle cross-sectional areas and strength in advanced versus early painful osteoarthritis-An exploratory between-knee, within-person comparison in osteoarthritis initiative participants.

Arthritis Care and Research 65:1034-1042 (2013)


Sattler M, Dannhauer T, Hudelmaier M, Wirth W, Sänger AM, Kwoh CK, Hunter DJ, Eckstein F

Side differences of thigh muscle cross-sectional areas and maximal isometric muscle force in bilateral knees with the same radiographic disease stage, but unilateral frequent pain - Data from the Osteoarthritis Initiative.
Osteoarthritis and Cartilage 20:532-540 (2012)


Hudelmaier M, Wirth W, Himmer M, Ring-Dimitriou S, Sänger A, Eckstein F
Effect of exercise intervention on thigh muscle volume and anatomical cross-sectional areas-Quantitative assessment using MRI.
Magnetic Resonance in Medicine 64:1713-1720 (2010)

Cotofana S, Hudelmaier M, Wirth W, Himmer M, Ring-Dimitriou S, Sänger AM, Eckstein F
Correlation between single-slice muscle anatomical cross-sectional area and muscle volume in thigh extensors, flexors and adductors of perimenopausal women.
European Journal of Applied Physiology 110:91-79 (2010)

Gratzke C, Hudelmaier M, Hitzl W, Glaser C, Eckstein F
Knee cartilage morphologic characteristics and muscle status of professional weight lifters and sprinters: a magnetic resonance imaging study.
American Journal of Sports Medicine 35:1346-1353 (2007)

Hudelmaier M, Glaser C, Hausschild A, Burgkart R, Eckstein F
Effects of joint unloading and reloading on human cartilage morphology and function, muscle cross-sectional areas, and bone density ? a quantitative case report.
Journal of Musculoskeletal Neuronal Interaction: 6: 284-290 (2006)

Hudelmaier M, Glaser C, Hohe J, Englmeier KH, Reiser M, Putz R, Eckstein F
Correlation of knee joint cartilage morphology with muscle cross-sectional areas versus anthropometric variables.
Anatomical Record 270: 175-184 (2003)





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