RESEARCH - ORIGINAL ARTICLES - CARTILAGE

• Mosher TJ, Zhang Z, Reddy R, Boudhar S, Milestone BN, Morrison WB, Kwoh CK, Eckstein F, Witschey WR, Borthakur A. Knee articular cartilage damage in osteoarthritis: analysis of MR image biomarker reproducibility in ACRIN-PA 4001 multicenter trial.
  Radiology. 2011 Jan 6. [Epub ahead of print]
  

• Inglis D, Wong AK, Eckstein F, Adachi JD, Beattie KA. Multiplanar reconstruction recovers morphological cartilage assessment reproducibility from maloriented coronal MRI scans.
  Magnetic Resonance in Medicine 2010 Oct 11. [Epub ahead of print]
  

• Hudelmaier M, Wirth W, Wehr B, Kraus V, Wyman BT, Hellio Le Graverand MP, Eckstein F.Femorotibial Cartilage Morphology: Reproducibility of Different Metrics and Femoral Regions, and Sensitivity to Change in Disease.
  Cells Tissues Organs 192(5):340-50 (2010)
  

• Wirth W, Nevitt M, Hellio Le Graverand MP, Benichou O, Dreher D, Davies RY, Lee J, Picha K, Gimona A, Maschek S, Hudelmaier M, Eckstein F; for the OAI investigators.Sensitivity to change of cartilage morphometry using coronal FLASH, sagittal DESS, and coronal MPR DESS protocols ? comparative data from the osteoarthritis initiative (OAI).
  Osteoarthritis and Cartilage 18(4):547-54 (2010)
  

• Wirth W, Benichou O, Kwoh CK, Guermazi A, Hunter D, Putz R, Eckstein F; for the OAI Investigators.Spatial patterns of cartilage loss in the medial femoral condyle in osteoarthritic knees: Data from the Osteoarthritis Initiative
  Osteoarthritis and Cartilage 63(3):574-81 (2010)
  

• Buck RJ, Wyman BT, Le Graverand MP, Wirth W, Eckstein F; for the A9001140 Investigators.An efficient subset of morphological measures for articular cartilage in the healthy and diseased human knee.
  Magnetic Resonance in Medicine 63(3):680-90 (2010)
  

• Eckstein F, Wyman BT, Buck RJ, Wirth W, Maschek S, Hudelmaier M, Hellio Le Graverand MP; 9001140 Study Group. Longitudinal quantitative MR imaging of cartilage morphology in the presence of gadopentetate dimeglumine (Gd-DTPA).
  Magnetic Resonance in Medicine 61(4):975-80 (2009)
  

• Wirth W, Eckstein FA technique for regional analysis of femorotibial cartilage thickness based on quantitative magnetic resonance imaging.
  IEEE Transactions of Medical Imaging 27:737-44 (2008)
  

• Eckstein F, Buck RJ, Burstein D, Charles HC, Crim J, Hudelmaier M, Hunter D, Hutchins G, Jackson C, Byers Kraus V, Lane NE, Link TM, Majumdar S, Mazzuca S,Prasad PV, Schnitzer TJ, Taljanovic MS, Vaz A, Wyman B, Hellio
  Le Graverand MP: Precision of 3.0 Tesla quantitative magnetic resonance imaging of cartilage morphology in a multi center clinical trial.
  Annals of Rheumatic Diseases 67:1683-8 (2008).
  

• Inglis D, Pui M, Ioannidis G, Beattie K, Boulos P, Adachi JD, Webber CE, Eckstein F
  Accuracy and test-retest precision of quantitative cartilage morphology on a 1.0 T peripheral magnetic resonance imaging system.
  Osteoarthritis and Cartilage. 15(1):110-5. (2007)
  

• Eckstein F, Buck RJ, Wyman BT, Kotyk JJ, Le Graverand MP, Remmers AE, Evelhoch JL, Hudelmaier M, Charles HC
  Quantitative imaging of cartilage morphology at 3.0 Tesla in the presence of gadopentate dimeglumine (Gd-DTPA).
  Magnetic Resonance in Medicine 58(2):402-6 (2007)
  

• Eckstein F, Ateshian G, Burgkart R, Burstein D, Cicuttini F, Dardzinski B, Gray M, Link TM, Majumdar S, Mosher T, Peterfy C, Totterman S, Waterton J, Winalski C, Felson D
  Proposal for a nomenclature for magnetic resonance imaging based measures of articular cartilage in osteoarthritis.
  Osteoarthritis and Cartilage 14 (10): 974-983 (2006)
  

• Eckstein F, Hudelmaier M, Wirth W, Kiefer B, Jackson R, Yu J, Eaton C, Schneider E
  Double Echo Steady State (DESS) magnetic resonance imaging of knee articular cartilage at 3 Tesla ? a pilot study for the Osteoarthritis Initiative.
  Annals of Rheumatic Diseases 65 (4): 433-41 (2006)
  

• Eckstein F, Buck R, Remmers A, Hudelmaier M, Wirth W, Krauss V, Charles C, Evelhoch J
  Accuracy and precision of quantitative assessment of cartilage status with 3.0 Tesla magnetic resonance imaging.
  Arthritis and Rheumatism 52(10): 3132-3136 (2005)
  

• Graichen H, Al-Shamari D, Hinterwimmer S, von Eisenhart-Rothe R, Vogl T, Eckstein F
  Accuracy of quantitative MRI in the detection of ex vivo focal cartilage defects.
  Annals of Rheumatic Diseases 64: 1120-5 (2005)
  

• McWalter EJ, Wirth W, Siebert M, von Eisenhart-Rothe RM, Hudelmaier M, Wilson DR, Eckstein F
  Use of novel interactive input devices for segmentation of articular cartilage from magnetic resonance images.
  Osteoarthritis and Cartilage 13(1):48-53 (2005)
  

• Graichen H, v. Eisenhart-Rothe R, Vogl T, Englmeier KH, Eckstein F
  Quantitative assessment of cartilage status in osteoarthritis by quantitative magnetic resonance imaging: technical validation for use in analysis of cartilage volume and further morphologic parameters.
  Arthritis and Rheumatism 50: 811?816 (2004)
  

• Graichen H., Jakob J., v. Eisenhart-Rothe R., Englmeier K.H., Reiser M., Eckstein F.
  Validation of cartilage thickness measurements in the human shoulder with quantitative magnetic resonance imaging (qMRI)
  Osteoarthritis and Cartilage 11: 475-482 (2003)
  

• Glaser C., Burgkart R., Kutschera A., Englmeier K.H., Reiser M., Eckstein F.
  Femoro-tibial cartilage metrics from coronal MR image data: technique, test-retest reproducibility, and findings in OA.
  Magnetic Resonance in Medicine 50: 1229-1236 (2003)
  

• Hohe J., Ateshian G., Reiser M., Englmeier K.-H., Eckstein F.
  Surface size, curvature analysis, and quantitative assessment of knee joint incongruity with MR imaging in vivo.
  Magnetic Resonance in Medicine 47: 554-561 (2002)
  

• Hohe J., Faber S., Mühlbauer R., Reiser M., Englmeier K.-H., Eckstein F.
  Three-dimensional analysis and visualization of regonal MR signal intensity distribution of articular cartilage.
  Medical Engineering and Physics 24: 219-227 (2002)
  

• Eckstein F., Heudorfer L., Faber S., Burgkart R., Englmeier K.-H., Reiser M.
  Long-term and resegmentation precision of quantitative cartilage MR imaging (qMRI)
  Osteoarthritis and Cartilage 10: 922 - 927 (2002)
  

• Glaser C, Faber S, Eckstein F, Fischer H, Springer V, Heudorfer L, Stammberger T, Englmeier K, Reiser M.
  Optimization and validation of a rapid high-resolution T1-w 3D Flash waterexcitation MR sequence for the quantitative assessment of articular cartilage volume and thickness.
  Magnetic Resonance Imaging 19: 177 -185 (2001)
  

• Burgkart R., Glaser C., Hyhlik-Dürr A., Englmeier K.-H., Reiser M., Eckstein F.
  MRI-based assessment of cartilage loss in severe osteoarthritis ? accuracy, precision, and diagnostic value.
  Arthritis and Rheumatism 44: 2072 - 2077 (2001)
  

• Eckstein F., Stammberger T., Priebsch J., Englmeier K.-H., Reiser M.
  Effect of gradient and section orientation on quantitative analyses of knee joint cartilage.
  Journal of Magnetic Resonance Imaging 11: 161 ? 167 (2000)
  

• Hyhlik-Dürr A., Faber S., Burgkart R., Stammberger T., Maag K.-P., Englmeier K.-H., Reiser M., Eckstein F.
  Precision of tibial cartilage morphometry with a coronal water-excitation MR-sequence.
  European Radiology 10: 297-303 (2000)
  

• Stammberger T., Hohe J., Englmeier K.-H., Reiser M., Eckstein F.
  Elastic registration of 3D cartilage surfaces from MR image data for detecting local changes of the cartilage thickness.
  Magnetic Resonance in Medicine 44: 592-601 (2000)
  

• Hohe J., Faber S., Stammberger T., Englmeier K.-H., Reiser M., Eckstein F.
  A technique for 3D in vivo quantification of proton density and magnetization transfer coefficients of knee joint cartilage.
  Osteoarthritis and Cartilage 8:426-433 (2000)
  

• Stammberger T., Eckstein F., Englmeier K.-H., Reiser M.
  Determination of 3D cartilage thickness data from MR imaging - computational method and reproducibility in the living.
  Magnetic Resonance in Medicine 41: 529 ? 536 (1999)
  

• Stammberger T., Eckstein F., Michaelis M., Englmeier K.-H., Reiser M.
  Interobserver reproducibility of quantitative cartilage measurements: comparsion between B-spline snakes and manual segmentation.
  Magnetic Resonance Imaging 17: 1033 ? 1042 (1999)
  

• Eckstein F., Westhoff J., Sittek H., Maag K.-P., Haubner M., Faber S., Englmeier K.-H., Reiser M.
  In vivo reproducibility of three-dimensional cartilage volume and thickness measurements with magnetic resonance imaging.
  American Journal of Radiology 170: 593 - 597 (1998)
  

• Herberhold C., Stammberger T., Faber S., Putz R., Englmeier K.-H., Reiser M., Eckstein F
  An MR-based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint.
  Magnetic Resonance in Medicine 39: 843 - 850 (1998)
  

• Eckstein F., Schnier M., Haubner M., Priebsch J., Glaser C., Englmeier K.-H., Reiser M.
  Accuracy of three-dimensional knee joint cartilage volume and thickness measurements with MRI.
  Clinical Orthopaedics and Related Research 352: 137 - 148 (1998)
  

• Stammberger T., Herberhold C., Faber S., Englmeier K.-H., Reiser M., Eckstein F.
  A method for quantifying time-dependent changes in MR signal intensity of articular cartilage as a function of tissue deformation in intact joints.
  Medical Engineering and Physics 20: 741 ? 749 (1998)
  

• Eckstein F., Adam C., Sittek H., Becker C., Milz S., Schulte E., Reiser M., Putz R.
  Non-invasive determination of cartilage thickness throughout joint surfaces using magnetic resonance imaging.
  Journal of Biomechanics 30: 285 - 289 (1997)
  

• Englmeier K.-H., Haubner M., Lösch A., Eckstein F., Seemann M.R., van Eimeren W., Reiser M.
  Hybrid rendering of multidimensional image data.
  Methods of Information in Medicine 36: 1 - 10 (1997)
  

• Lösch A., Eckstein F., Haubner M., Englmeier K.-H.
  A non-invasive technique for 3-dimensional assessment of articular cartilage thickness based on MRI - Part I: development of a computational method.
  Magnetic Resonance Imaging 15: 795 - 804 (1997)
  

• Haubner M., Eckstein F., Lösch A., Schnier M., Sittek H., Becker C., Kolem H., Reiser M., Englmeier KH.
  A non-invasive technique for 3-dimensional assessment of articular cartilage thickness based on MRI -Part II: Validation with CT arthrography.
  Magnetic Resonance Imaging 15: 805 - 813 (1997)
  

• Tieschky M., Faber S., Haubner M., Kolem H., Schulte E., Englmeier K.-H., Reiser M., Eckstein F
  Repeatability of patellar cartilage thickness patterns in the living, using a fat-suppressed MRI sequence with short acquisition time and 3D data processing.
  Journal of Orthopaedic Research 15: 808 - 813 (1997)
  

• Eckstein F., Sittek H., Gavazzeni A., Schulte E., Kiefer B., Milz S., Reiser M., Putz R.
  Magnetic resonance chondro-crassometry (MR-CCM) : a method for accurate determination of articular cartilage thickness?
  Magnetic Resonance in Medicine 35: 89 - 96 (1996)
  

• Sittek H., Eckstein F., Gavazzeni A., Milz S., Kiefer B., Schulte E., Reiser M.
  Assessment of normal patellar cartilage volume and thickness using MRI: an analysis of currently available pulse sequences.
  Skeletal Radiology 25: 55 - 62 (1996)
  

• Eckstein F., Merz B., Sittek H., Kolem H., Reiser M., Putz R.
  Geometry-to-pressure relationship in the human elbow joint - a qualitative analysis using MRI and finite elements.
  European Journal of Anatomy 1: 23 - 30 (1996)
  

• Eckstein F., Gavazzeni A., Sittek H., Haubner M., Lösch A., Milz S., Englmeier K.-H., Schulte E., Putz R., Reiser M
  Determination of knee-joint cartilage thickness using three-dimensional magnetic resonance chondro-crassometry (3D MR-CCM).
  Magnetic Resonance in Medicine 36: 256 - 265 (1996)
  

• Münsterer O., Eckstein F., Hahn D., Putz R.
  Computer-aided 3D assessment of knee joint cartilage with magnetic resonance imaging.
  Clinical Biomechanics 11: 260 - 266 (1996)
  

• Eckstein F., Sittek H., Milz S., Schulte E., Kiefer B., Reiser M., Putz R.
  The potential of magnetic resonance imaging (MRI) for quantifying articular cartilage thickness - a methodological study.
  Clinical Biomechanics 10: 434 - 440 (1995)
  

• Eckstein F., Sittek H., Milz S., Putz R., Reiser M.
  The morphology of articular cartilage assessed by magnetic resonance imaging (MRI) - Reproducibility and anatomical correlation.
  Surgical and Radiologic Anatomy 16: 429 - 438 (1994)
  

• Buck RJ, Wyman BT, Helliole Graverand MP, Hunter D, Vignon E, Wirth W, Eckstein F.
  Using ordered values of subregional cartilage thickness change increases sensitivity in detecting risk factors for osteoarthritis progression.
  Osteoarthritis Cartilage. 2010 Dec 22. [Epub ahead of print]
  

• Moisio K, Chang A, Eckstein F, Chmiel JS, Wirth W, Almagor O, Prasad P, Cahue S, Kothari A, Sharma L.
  Varus-valgus alignment: Reduced risk for subsequent cartilage loss in the less loaded compartment.
  Arthritis and Rheumatism 2011 Jan 10. [Epub ahead of print]
  

• Wirth W, Larroque S, Davies RY, Nevitt M, Gimona A, Baribaud F, Lee JH, Benichou O, Wyman BT, Hudelmaier M, Maschek S, Eckstein F; for the OA Initiative Investigators Group.
  Comparison of One-Year Versus Two-year Change in Regional Cartilage Thickness in Osteoarthritis Results from 346 Participants From the Osteoarthritis Initiative.
  Osteoarthritis and Cartilage 19(1): 74-83 ( 2011)
  

• Eckstein F, Nevitt M, Gimona A, Picha K, Lee JH, Davies RY, Dreher D, Benichou O, Le Graverand MP, Hudelmaier M, Maschek S, Wirth W; for the OA Initiative investigators Group.
  Rates of change and sensitivity to change in cartilage morphology in healthy knees and in knees with mild, moderate, and end stage radiographic osteoarthritis.
  Arthritis Care and Research (Hoboken). 2010 Oct 18. [Epub ahead of print]
  

• Chang A, Moisio K, Chmiel JS, Eckstein F, Guermazi A, Almagor O, Cahue S, Wirth W, Prasad P, Sharma L.
  Subregional effects of meniscal tears on cartilage loss over 2 years in knee osteoarthritis.
  Annals of Rheumatic Diseases 70(1): 74-9 (2011)
  

• Eckstein F, Yang M, Guermazi A, Roemer FW, Hudelmaier M, Picha K, Baribaud F, Wirth W, Felson DT.
  Reference values and Z-scores for subregional femorotibial cartilage thickness - results from a large population-based sample (Framingham) and comparison with the non-exposed Osteoarthritis Initiative reference cohort.
  Osteoarthritis and Cartilage 18(10):1275-83 (2010)
  

• Benichou OD, Hunter DJ, Nelson DR, Guermazi A, Eckstein F, Kwoh K, Myers SL, Wirth W, Duryea J; Osteoarthritis Initiative Investigators.One-year change in radiographic joint space width in patients with unilateral joint space narrowing: data from the Osteoarthritis Initiative.
  Arthritis Care and Research 62(7):924-31 (2010)
  

• Frobell RB, Nevitt MC, Hudelmaier M, Wirth W, Wyman BT, Benichou O, Dreher D, Davies R, Lee JH, Baribaud F, Gimona A, Eckstein F; for the OA Initiative investigators.
  Femorotibial subchondral bone area and regional cartilage thickness - a cross-sectional description in healthy reference cases and various radiographic stages of osteoarthritis in 1003 knees from the Osteoarthritis Initiative.
  Arthritis Care and Research 62(11):1612-23 (2010)
  

• Frobell RB, Wirth W, Nevitt M, Wyman BT, Benichou O, Dreher D, Davies RY, Lee JH, Baribaud F, Gimona A, Hudelmaier M, Cotofana S, Eckstein F; for the OA Initiative Investigators.
  Presence, location type, and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA ? data from the OA Initiative.
  Osteoarthritis and Cartilage 18 (5):668-79 (2010)
  

• Vanwanseele B, Eckstein F, Smith RM, Lange AK, Foroughi N, Baker MK, Shnier R, Fiatarone Singh MA.
  The relationship between knee adduction moment and cartilage and meniscus morphology in women with osteoarthritis.
  Osteoarthritis and Cartilage 18(7):894-901 (2010)
  

• Buck RJ, Wyman BT, Hellio Le Graverand MP, Hudelmaier M, Wirth W, Eckstein F; for the A 9001140 investigators.
  Osteoarthritis may not be a one-way-road of cartilage loss ? comparison of spatial patterns of cartilage change between osteoarthritic and healthy knees
  Osteoarthritis and Cartilage 18(3):329-35 (2010)
  

• Crema MD, Guermazi A, Li L, Nogueira-Barbosa MH, Marra MD, Roemer FW, Eckstein F, Hellio Le Graverand MP, Wyman BT, Hunter DJ. The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period.
  Osteoarthritis and Cartilage 18(3):336-43 (2010)
  

• Eckstein F, Wirth W, Hunter DJ, Guermazi A, Kwoh CK, Nelson DR, Benichou O; OAI Investigators.
  Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis ? data from the Osteoarthritis Initiative (OAI).
  Osteoarthritis and Cartilage 18(6):760-8 (2010)
  

• Reichenbach S, Yang M, Eckstein F, Niu J, Hunter DJ, McLennan CE, Guermazi A, Roemer FW, Hudelmaier M, Aliabadi P, Felson DT.Does cartilage volume or thickness distinguish knees with and without mild radiographic osteoarthritis? The Framingham Study.
  Annals of Rheumatic Diseases 69 (1):143-9 (2010)
  

• Hellio Le Graverand MP, Buck RJ, Wyman BT, Vignon E, Mazzuca SA, Brandt KD, Piperno M, Charles HC, Hudelmaier M, Hunter DJ, Jackson C, Kraus VB, Link TM, Majumdar S, Prasad PV, Schnitzer TJ, Vaz A, Wirth W, Eckstein F.
  Change in regional cartilage morphology and joint space width in osteoarthritis participants versus healthy controls - a multicenter study using 3.0 Tesla MRI and Lyon Schuss radiography.
  Annals of Rheumatic Diseases 69 (1): 155-62 (2010)
  

• Moisio K, Eckstein F, Chmiel JS, Guermazi A, Prasad P, Almagor O, Song J, Dunlop D, Hudelmaier M, Kothari A, Sharma L Denuded subchondral bone and knee pain in persons with knee osteoarthritis Arthritis and Rheumatism 60(12): 3703-10 (2009)Messier SP, Legault C, Mihalko S, Miller GD, Loeser RF, DeVita P, Lyles M, Eckstein F, Hunter DJ, Williamson JD, Nicklas BJ
  The intensive diet and exercise for arthritis (IDEA) trial: design and rationale
  BMC Musculoskeletal Disorders 10:93 (2009)
  

• Eckstein F, Benichou O, Wirth W, Nelson DR, Maschek S, Hudelmaier M, Kwoh CK, Guermazi A, Hunter D.Magnetic resonance imaging-based cartilage loss in painful contralateral knees with and without radiographic joint space narrowing: data from the osteoarthritis initiative
  Arthritis and Rheumatism 61(9): 1218-25 (2009)
  

• Hunter DJ, Buck R, Vignon E, Eckstein F, Brandt K, Mazzuca SA, Wyman BT, Otterness I, Hellio Le Graverand MP. Relation of regional articular cartilage morphometry and meniscal position by MRI joint space width in knee radiographs.
  Osteoarthritis and Cartilage 17(9):1170-6 (2009)
  

• Eckstein F, Wirth W, Hudelmaier M, Maschek S, Hitzl W, Wyman BT, Nevitt M, Hellio Le Graverand MP, Hunter D; the OA Initiative Investigator Group.Relationship of compartment-specific structural knee status at baseline with change in cartilage morphology: a prospective observational study using data from the osteoarthritis initiative
  Arthritis Research and Therapy 11(3):R90 (2009)
  

• Hellio Le Graverand MP, Buck RJ, Wyman BT, Vignon E, Mazzuca SA, Brandt KD, Piperno M, Charles HC, Hudelmaier M, Hunter DJ, Jackson C, Kraus VB, Link TM, Majumdar S, Prasad PV; Schnitzer TJ, Vaz A, Wirth W, Eckstein F.Subregional femorotibial cartilage morphology in women ? comparison between healthy controls and participants with different grades of radiographic knee osteoarthritis.
  Osteoarthritis and Cartilage 17(9):1177-85 (2009)
  

• Andreisek G, White LM, Sussman MS, Kunz M, Hurtig M, Weller I, Essue J, Marks P, Eckstein F. Quantitative MR imaging evaluation of the cartilage thickness and subchondral bone area in patients with ACL-reconstructions 7 years after surgery.
  Osteoarthritis and Cartilage 17(7):871-8 (2009)
  

• Eckstein F, Maschek S, Wirth W, Hudelmaier M, Hitzl W, Wyman B, Nevitt M, Hellio Le Graverand MP. One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort - association with sex, body mass index, symptoms, and radiographic OA status.
  Annals of Rheumatic Diseases 68 (5):674-9 (2009)
  

• Wirth W, Hellio Le Graverand MP, Wyman BT, Maschek S, Hudelmaier M, Hitzl W, Nevitt M, Eckstein F, the OAI Investigator Group. Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort.
  Osteoarthritis and Cartilage 17(3): 291-7 (2009)
  

• Eckstein F, Wirth W, Hudelmaier M, Stein V, Lengfelder V, Cahue S, Marshall M, Prasad P, Sharma LPatterns of femorotibial cartilage loss in knees with neutral, varus, and valgus alignment.
  Arthritis Rheum. 59:1563-70 (2008).
  

• Beattie KA, Duryea J, Pui M, O´Neill J, Boulos P, Webber CE, Eckstein F, Adachi JD
  Minimum joint space width and tibial cartilage morphology in the knees of healthy individuals: a cross-sectional study.
  BMC Musculoskelet Disord. 9:119 (2008).
  

• Sharma L, Eckstein F, Song J, Guermazi A, Prasad P, Kapoor D, Cahue S, Marshall M, Hudelmaier M, Dunlop D
  Relationship of meniscal damage, meniscal extrusion, malalignment, and joint laxity to subsequent cartilage loss in osteoarthritic knees.
  Arthritis Rheum 58:1716-26 (2008)
  

• Hunter DJ, Niu J, Zhang Y, Lavalley M, McClennan CE, Hudelmaier M, Eckstein F, Felson DT
  Premorbid knee OA is not characterized by diffuse thinness: The Framingham Study.
  Ann Rheum Dis. 67:1545-9 (2008).
  

• Otterness IG, Le Graverand MP, Eckstein F
  Allometric relationships between knee cartilage volume, thickness, surface area and body dimensions.
  Osteoarthritis Cartilage. 16:34-40 (2008).
  

• Eckstein F, Kunz M, Schutzer M, Hudelmaier M, Jackson RD, Yu J, Eaton CB, Schneider E
  Two year longitudinal change and test-retest-precision of knee cartilage morphology in a pilot study for the osteoarthritis initiative.
  Osteoarthritis Cartilage 15(11):1326-32 (2007).
  

• Gratzke C, Hudelmaier M, Hitzl W, Glaser C, Eckstein F
  Knee cartilage morphologic characteristics and muscle status of professional weight lifters and sprinters: a magnetic resonance imaging study.
  Am J Sports Med. 35(8):1346-53 (2007)
  

• Otterness IG, Eckstein F
  Women have thinner cartilage and smaller joint surfaces than men after adjustment for body height and weight.
  Osteoarthritis Cartilage. 15(6):666-72 (2007)
  

• Eckstein F, Kunz M, Hudelmaier M, Jackson R, Yu J, Eaton C, Schneider E
  Impact of coil design on the contracts-to-noise, precision and consistency of quantitative cartilage morphometry at 3 Tesla ? a Pilot Study for the Osteoarthritis Initiative
  Magnetic Resonance in Medicine: 57(2): 448-454 (2007)
  

• Hudelmaier M, Glaser C, Hausschild A, Burgkart R, Eckstein F
  Effects of joint unloading and reloading on human cartilage morphology and function, muscle cross-sectional areas, and bone density ? a quantitative case report.
  Journal of Musculoskeletal and Neuronal Interactions: 6(3): 284-290 (2006)
  

• von Eisenhart-Rothe R, Graichen H, Hudelmaier M, Vogl T, Sharma L, Eckstein F
  Femorotibial and patellar cartilage loss in patients prior to total knee arthroplasty, heterogeneity and correlation with alignment of the knee.
  Annals of Rheumatic Diseases 65(1): 69-73 (2006)
  

• Hinterwimmer S, Gotthardt M, von Eisenhart-Rothe R, Sauerland S, Siebert M, Vogl T, Eckstein F, Graichen H
  In vivo contact areas of the knee in patients with patellar subluxation.
  Journal of Biomechanics 38(10):2095-2101 (2005)
  

• Eckstein F, Lemberger B, Gratzke C, Hudelmaier M, Glaser C, Englmeier K-H, Reiser M
  In vivo cartilage deformation after different types of activity and its dependence on physical training status.
  Annals of Rheumatic Diseases 64: 291-295 (2005)
  

• von Eisenhart-Rothe R, Bringmann C, Siebert M, Reiser M, Englmeier KH, Eckstein F, Graichen H
  Femoro-tibial and menisco-tibial translation patterns in patients with unilateral anterior cruciate ligament deficiency-a potential cause of secondary meniscal tears.
  Journal of Orthopaedic Research 22: 275-282 (2004)
  

• Vanwanseele B, Eckstein F, Hadwighorst H, Knecht H, Stüssi E, Spaepen A
  In vivo precision of quantitative shoulder cartilage measurements and changes after spinal cord injury.
  Magnetic Resonance in Medicine 51: 1026-1030 (2004)
  

• Eckstein F, Siedek V, Glaser C, Al-Ali D, Englmeier KH, Reiser M, Graichen H
  Correlation and sex differences of ankle and knee cartilage morphology determined with quantitative magnetic resonance imaging (qMRI).
  Annals of Rheumatic Diseases 63: 1490-1495 (2004)
  

• Hinterwimmer S, Krammer M, Krötz M, Glaser C, Baumgart R, Reiser M, Eckstein F
  Cartilage atrophy in the knees of patients after seven weeks of partial load bearing.
  Arthritis and Rheumatism 50: 2516-2520 (2004)
  

• Hudelmaier M., Glaser C., Hohe J., Englmeier K.H., Reiser M., Putz R., Eckstein F.
  Correlation of knee joint cartilage morphology with muscle cross-sectional areas versus anthropometric variables.
  Anatomical Record 270: 175-184 (2003)
  

• Burgkart R., Glaser C., Hinterwimmer S., Hudelmaier M., Englmeier K.H., Reiser M., Eckstein F.
  Feasibility of T- and Z-scores from MR image data for quantifying cartilage loss in osteoarthritis.
  Arthritis and Rheumatism 48: 2829-2835 (2003)
  

• Eckstein F., Faber S., Mühlbauer R., Hohe J.,,Englmeier K.-H., Reiser M., Putz R.
  Functional adaptation of human joints to mechanical stimuli.
  Osteoarthritis and Cartilage 10: 44-50 (2002)
  

• Al-Ali D., Graichen H. , Faber S.C. , Englmeier K.- H., Reiser M.
  Quantitative cartilage imaging in the human hind foot. Normal values and precision.
  Journal of Orthopaedic Research 20: 249-256 (2002)
  

• Vanwanseele B., Eckstein F., Knecht H., Stüssi E., Spaepen A.
  Knee cartilage of spinal cord injured patients displays progressive thinning in the absence of normal joint loading and movement.
  Arthritis and Rheumatism 46: 2073 ? 2078 (2002)
  

• Eckstein F., Müller S., Faber S., Englmeier K.-H., Reiser M., Putz R.
  Side differences of knee joint cartilage morphology as a function of lower limb dominance.
  Osteoarthritis and Cartilage 10: 914 - 921 (2002)
  

• Eckstein F., Winzheimer M., Hohe J., Englmeier K.-H., Reiser M.
  Interindividual variability and correlation among morphological parameters of knee joint cartilage plates.
  Osteoarthritis and Cartilage 9: 101-111 (2001)
  

• Faber S.C. , Eckstein F., Lukasz S., Mühlbauer R., Hohe J., Englmeier K.- H., Reiser M.
  Gender differences of knee joint cartilage thickness, volume and articular surface areas - assessment with quantitative 3D MR imaging:
  Skeletal Radiology 30: 144 ? 150 (2001)
  

• Hudelmaier M., Glaser C., Hohe J., Englmeier K.H., Reiser M., Putz R., Eckstein F.
  Age-related changes in the morphology and deformational behavior of knee joint cartilage.
  Arthritis and Rheumatism 44: 2556 - 2561 (2001)
  

• Eckstein F., Lemberger B., Stammberger T., Englmeier K.-H. Reiser M.
  Effect of static versus dynamic in vivo loading exercises on human patellar cartilage.
  Journal of Biomechanics 33: 819 ? 825 (2000)
  

• Mühlbauer R., Lukasz S., Faber S., Stammberger T., Eckstein F.
  Comparison of knee joint cartilage thickness in triathletes and physically inactive volunteers - 3D analysis with magnetic resonance imaging.
  American Journal of Sports Medicine 28: 541 ? 546 (2000)
  

• Eckstein F., Tieschky M., Faber S., Englmeier K.-H., Reiser M.
  Functional analysis of articular cartilage deformation, recovery, and fluid flow following dynamic exercise in vivo.
  Anatomy and Embryology 200: 419 ? 424 (1999)
  

• Herberhold C., Faber S., Stammberger T., Steinlechner M., Putz R., Englmeier K.-H., Reiser M., Eckstein F.
  In situ measurement of articular cartilage deformation in intact femoropatellar joints under static loading.
  Journal of Biomechanics 32: 1287 ? 1295 (1999)
  

• Eckstein F., Tieschky M., Faber S., Haubner M., Kolem H., Englmeier K.-H., Reiser M
  Effects of physical exercise on cartilage volume and thickness in vivo - an MR imaging study.
  Radiology 207: 243 - 248 (1998)
  

• Eckstein F., Winzheimer M., Westhoff J., Schnier M., Haubner M., Englmeier K.-H., Reiser M., Putz R.
  Quantitative relationships of normal cartilage volumes of the human knee joint - assessment by magnetic resonance imaging.
  Anatomy and Embryology 197: 383 - 390 (1998)